15 gallons per person in 2011, according to figures from the Florida Department of Citrus. Illicit Distribution: Hydrocodone has been encountered in tablets, capsules and, liquid form in the illicit market. Sometimes viewed as a white collar addiction, hydrocodone abuse has increased among all ethnic and economic groups. 44 gallons of juice per person per year in 2000 to. hydrocodone availability and the perceived safety of these products by medical prescribers. Consumption of grapefruit juice has dropped in the past decade, falling from. Some grapefruit lovers may have cut back already because of the risk of drug interaction. And doctors should make sure to ask about grapefruit consumption when prescribing drugs. Patients worried about the interaction of grapefruit with their medications should talk with their doctors, Bailey said. “These are the individuals with the greatest chance of exposure," he said. Seniors older than 70 have the most trouble tolerating excessively high levels of drugs, Bailey noted. Part of the concern lies in the fact that people older than 45 are most likely to consume grapefruit juice - and to take prescription drugs. “For every case report, there are at least 100 that have never been reported,” he said. It’s not clear how many people actually are harmed by grapefruit interactions, mostly because the side effects are often not recognized as being related to the citrus, said Bailey, who included eight case reports in his study. “I’ve seen a 10-fold increase in some patients,” Bailey said. The trouble with grapefruit has been known for two decades, ever since Bailey and his colleagues first discovered that ingestion of the fruit with certain prescription drugs can concentrate the medication in a patient’s bloodstream.ĭrinking less than a cup of grapefruit juice once a day for three days, for instance, can lead to a 330 percent concentration of simvastatin, the researchers reported. To see a complete list of drugs that interact with grapefruit, click here. Mixing the prescription painkiller oxycodone with grapefruit can cause serious breathing problems, and adding the fruit to a dose of the popular statin simvastatin, or Zocor, can lead to rhabdomyolysis, a breakdown of muscle fibers that can lead to kidney damage. The heart drug dronedarone, or Multaq, for instance, has a very high risk of interaction when taken with grapefruit, which may cause a rare form of ventricular tachycardia or rapid heart rhythm, the researchers found.
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